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Immune Cytolytic Activity for Comprehensive Understanding of Immune Landscape in Hepatocellular Carcinoma

Cytolytic activity score (CYT), defined by granzyme A and perforin expression, is a useful marker for underlying immunity. We hypothesized that CYT-high hepatocellular carcinomas (HCCs) have stronger immunogenicity and favorable tumor microenvironments, which would result in better clinical outcomes...

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Detalles Bibliográficos
Autores principales: Takahashi, Hideo, Kawaguchi, Tsutomu, Yan, Li, Peng, Xuan, Qi, Qianya, Morris, Luc G.T., Chan, Timothy A., Tsung, Allan, Otsuji, Eigo, Takabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281225/
https://www.ncbi.nlm.nih.gov/pubmed/32414098
http://dx.doi.org/10.3390/cancers12051221