PEDV ORF3 Independently Regulates IκB Kinase β-Mediated NF-κB and IFN-β Promoter Activities

The Open Reading Frame 3 (ORF3), an accessory protein of porcine epidemic diarrhea virus (PEDV), has been shown to interact with a myriad of cellular proteins, among which include the IκB kinase β (IKBKB). Here, specific IKBKB domains responsible for ORF3–IKBKB interaction were identified. Dysregula...

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Detalles Bibliográficos
Autores principales: Kaewborisuth, Challika, Koonpaew, Surapong, Srisutthisamphan, Kanjana, Viriyakitkosol, Ratchanont, Jaru-ampornpan, Peera, Jongkaewwattana, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281231/
https://www.ncbi.nlm.nih.gov/pubmed/32423021
http://dx.doi.org/10.3390/pathogens9050376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281231/
https://www.ncbi.nlm.nih.gov/pubmed/32423021
http://dx.doi.org/10.3390/pathogens9050376

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