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Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer

Cancer has been conceptualized as a chronic wound with a predominance of tumor promoting inflammation. Given the accumulating evidence that the microenvironment supports tumor growth, we investigated hyaluronan (HA)-CD44 interactions within breast cancer cells, to determine whether this axis directl...

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Detalles Bibliográficos
Autores principales: Witschen, Patrice M., Chaffee, Thomas S., Brady, Nicholas J., Huggins, Danielle N., Knutson, Todd P., LaRue, Rebecca S., Munro, Sarah A., Tiegs, Lyubov, McCarthy, James B., Nelson, Andrew C., Schwertfeger, Kathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281239/
https://www.ncbi.nlm.nih.gov/pubmed/32455980
http://dx.doi.org/10.3390/cancers12051325