Cargando…
Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer
Cancer has been conceptualized as a chronic wound with a predominance of tumor promoting inflammation. Given the accumulating evidence that the microenvironment supports tumor growth, we investigated hyaluronan (HA)-CD44 interactions within breast cancer cells, to determine whether this axis directl...
Autores principales: | Witschen, Patrice M., Chaffee, Thomas S., Brady, Nicholas J., Huggins, Danielle N., Knutson, Todd P., LaRue, Rebecca S., Munro, Sarah A., Tiegs, Lyubov, McCarthy, James B., Nelson, Andrew C., Schwertfeger, Kathryn L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281239/ https://www.ncbi.nlm.nih.gov/pubmed/32455980 http://dx.doi.org/10.3390/cancers12051325 |
Ejemplares similares
-
Erratum: Witschen, P.M., et al. Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer. Cancers 2020, 12, 1325
por: Witschen, Patrice M., et al.
Publicado: (2020) -
Characterization of Hyaluronan Localization in the Developing Mammary Gland and Mammary Tumors
por: Witschen, Patrice M., et al.
Publicado: (2023) -
Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice
por: Wang, Ying, et al.
Publicado: (2020) -
ADAM17 in tumor associated leukocytes regulates inflammatory mediators and promotes mammary tumor formation
por: Bohrer, Laura R., et al.
Publicado: (2016) -
STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment
por: Jesser, Emily A., et al.
Publicado: (2021)