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Autotransporter-Mediated Display of Complement Receptor Ligands by Gram-Negative Bacteria Increases Antibody Responses and Limits Disease Severity

The targeting of immunogens/vaccines to specific immune cells is a promising approach for amplifying immune responses in the absence of exogenous adjuvants. However, the targeting approaches reported thus far require novel, labor-intensive reagents for each vaccine and have primarily been shown as p...

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Detalles Bibliográficos
Autores principales: Holland-Tummillo, Kristen M, Shoudy, Lauren E, Steiner, Donald, Kumar, Sudeep, Rosa, Sarah J, Namjoshi, Prachi, Singh, Anju, Sellati, Timothy J, Gosselin, Edmund J, Hazlett, Karsten RO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281241/
https://www.ncbi.nlm.nih.gov/pubmed/32422907
http://dx.doi.org/10.3390/pathogens9050375