Suicide Gene Therapy Mediated with Exosomes Produced by Mesenchymal Stem/Stromal Cells Stably Transduced with HSV Thymidine Kinase

Mesenchymal stem/stromal cells (MSCs) prepared from various human tissues were stably transduced with the suicide gene herpes simplex virus thymidine kinase (HSVTK) by means of retrovirus infection. HSVTK-transduced MSCs express the suicide gene and in prodrug ganciclovir (GCV) presence induced cell...

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Detalles Bibliográficos
Autores principales: Pastorakova, Andrea, Jakubechova, Jana, Altanerova, Ursula, Altaner, Cestmir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281242/
https://www.ncbi.nlm.nih.gov/pubmed/32354013
http://dx.doi.org/10.3390/cancers12051096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281242/
https://www.ncbi.nlm.nih.gov/pubmed/32354013
http://dx.doi.org/10.3390/cancers12051096

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