T Cells Expressing a TCR-Like Antibody Selected Against the Heteroclitic Variant of a Shared MAGE-A Epitope Do Not Recognise the Cognate Epitope

Antibodies-recognising peptides bound to the major histocompatibility complex (pMHC) represent potentially valuable and promising targets for chimeric antigen receptor (CAR) T cells to treat patients with cancer. Here, a human phage-Fab library has been selected using HLA-A2 complexed with a heteroc...

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Detalles Bibliográficos
Autores principales: Saeed, Mesha, Schooten, Erik, van Brakel, Mandy, K. Cole, David, ten Hagen, Timo L. M., Debets, Reno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281252/
https://www.ncbi.nlm.nih.gov/pubmed/32429338
http://dx.doi.org/10.3390/cancers12051255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281252/
https://www.ncbi.nlm.nih.gov/pubmed/32429338
http://dx.doi.org/10.3390/cancers12051255

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