Single-Cell Transcriptomic Analysis of Tumor-Derived Fibroblasts and Normal Tissue-Resident Fibroblasts Reveals Fibroblast Heterogeneity in Breast Cancer

Cancer-associated fibroblasts (CAFs) are a prominent stromal cell type in solid tumors and molecules secreted by CAFs play an important role in tumor progression and metastasis. CAFs coexist as heterogeneous populations with potentially different biological functions. Although CAFs are a major compo...

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Detalles Bibliográficos
Autores principales: Sebastian, Aimy, Hum, Nicholas R., Martin, Kelly A., Gilmore, Sean F., Peran, Ivana, Byers, Stephen W., Wheeler, Elizabeth K., Coleman, Matthew A., Loots, Gabriela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281266/
https://www.ncbi.nlm.nih.gov/pubmed/32455670
http://dx.doi.org/10.3390/cancers12051307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281266/
https://www.ncbi.nlm.nih.gov/pubmed/32455670
http://dx.doi.org/10.3390/cancers12051307

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