Cargando…

Molecular Mechanisms of the Teratogenic Effects of Thalidomide

Thalidomide was sold worldwide as a sedative over 60 years ago, but it was quickly withdrawn from the market due to its teratogenic effects. Thalidomide was later found to have therapeutic effects in several diseases, although the molecular mechanisms remained unclear. The discovery of cereblon (CRB...

Descripción completa

Detalles Bibliográficos
Autores principales: Asatsuma-Okumura, Tomoko, Ito, Takumi, Handa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281272/
https://www.ncbi.nlm.nih.gov/pubmed/32414180
http://dx.doi.org/10.3390/ph13050095