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Molecular Mechanisms of the Teratogenic Effects of Thalidomide
Thalidomide was sold worldwide as a sedative over 60 years ago, but it was quickly withdrawn from the market due to its teratogenic effects. Thalidomide was later found to have therapeutic effects in several diseases, although the molecular mechanisms remained unclear. The discovery of cereblon (CRB...
Autores principales: | Asatsuma-Okumura, Tomoko, Ito, Takumi, Handa, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281272/ https://www.ncbi.nlm.nih.gov/pubmed/32414180 http://dx.doi.org/10.3390/ph13050095 |
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