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DFIQ, a Novel Quinoline Derivative, Shows Anticancer Potential by Inducing Apoptosis and Autophagy in NSCLC Cell and In Vivo Zebrafish Xenograft Models

Lung cancer is one of the deadliest cancers worldwide due to chemoresistance in patients with late-stage disease. Quinoline derivatives show biological activity against HIV, malaria, bacteriuria, and cancer. DFIQ is a novel synthetic quinoline derivative that induces cell death in both in vitro and...

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Detalles Bibliográficos
Autores principales: Huang, Hurng-Wern, Bow, Yung-Ding, Wang, Chia-Yih, Chen, Yen-Chun, Fu, Pei-Rong, Chang, Kuo-Feng, Wang, Tso-Wen, Tseng, Chih-Hua, Chen, Yeh-Long, Chiu, Chien-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281296/
https://www.ncbi.nlm.nih.gov/pubmed/32466291
http://dx.doi.org/10.3390/cancers12051348