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A Novel 4-gene Score to Predict Survival, Distant Metastasis and Response to Neoadjuvant Therapy in Breast Cancer

We generated a 4-gene score with genes upregulated in LM2-4, a metastatic variant of MDA-MB-231 (DOK 4, HCCS, PGF, and SHCBP1) that was strongly associated with disease-free survival (DFS) in TCGA cohort (hazard ratio [HR]>1.2, p < 0.02). The 4-gene score correlated with overall survival of TC...

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Detalles Bibliográficos
Autores principales: Oshi, Masanori, Katsuta, Eriko, Yan, Li, Ebos, John M.L., Rashid, Omar M., Matsuyama, Ryusei, Endo, Itaru, Takabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281399/
https://www.ncbi.nlm.nih.gov/pubmed/32370309
http://dx.doi.org/10.3390/cancers12051148