Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action

We have earlier reported anticancer activity in Withaferin A (Wi-A), a withanolide derived from Ashwagandha (Withania somnifera) and caffeic acid phenethyl ester (CAPE), an active compound from New Zealand honeybee propolis. Whereas Wi-A was cytotoxic to both cancer and normal cells, CAPE has been s...

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Detalles Bibliográficos
Autores principales: Sari, Anissa Nofita, Bhargava, Priyanshu, Dhanjal, Jaspreet Kaur, Putri, Jayarani F., Radhakrishnan, Navaneethan, Shefrin, Seyad, Ishida, Yoshiyuki, Terao, Keiji, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281427/
https://www.ncbi.nlm.nih.gov/pubmed/32380701
http://dx.doi.org/10.3390/cancers12051160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281427/
https://www.ncbi.nlm.nih.gov/pubmed/32380701
http://dx.doi.org/10.3390/cancers12051160

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