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Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action
We have earlier reported anticancer activity in Withaferin A (Wi-A), a withanolide derived from Ashwagandha (Withania somnifera) and caffeic acid phenethyl ester (CAPE), an active compound from New Zealand honeybee propolis. Whereas Wi-A was cytotoxic to both cancer and normal cells, CAPE has been s...
Autores principales: | Sari, Anissa Nofita, Bhargava, Priyanshu, Dhanjal, Jaspreet Kaur, Putri, Jayarani F., Radhakrishnan, Navaneethan, Shefrin, Seyad, Ishida, Yoshiyuki, Terao, Keiji, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281427/ https://www.ncbi.nlm.nih.gov/pubmed/32380701 http://dx.doi.org/10.3390/cancers12051160 |
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