Challenging a “Cushy” Life: Potential Roles of Thermogenesis and Adipose Tissue Adaptations in Delayed Aging of Ames and Snell Dwarf Mice

Laboratory mouse models with genetically altered growth hormone (GH) signaling and subsequent endocrine disruptions, have longer lifespans than control littermates. As such, these mice are commonly examined to determine the role of the somatotropic axis as it relates to healthspan and longevity in m...

Descripción completa

Detalles Bibliográficos
Autores principales: Valencak, Teresa G., Spenlingwimmer, Tanja, Nimphy, Ricarda, Reinisch, Isabel, Hoffman, Jessica M., Prokesch, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281452/
https://www.ncbi.nlm.nih.gov/pubmed/32365727
http://dx.doi.org/10.3390/metabo10050176