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Challenging a “Cushy” Life: Potential Roles of Thermogenesis and Adipose Tissue Adaptations in Delayed Aging of Ames and Snell Dwarf Mice
Laboratory mouse models with genetically altered growth hormone (GH) signaling and subsequent endocrine disruptions, have longer lifespans than control littermates. As such, these mice are commonly examined to determine the role of the somatotropic axis as it relates to healthspan and longevity in m...
Autores principales: | Valencak, Teresa G., Spenlingwimmer, Tanja, Nimphy, Ricarda, Reinisch, Isabel, Hoffman, Jessica M., Prokesch, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281452/ https://www.ncbi.nlm.nih.gov/pubmed/32365727 http://dx.doi.org/10.3390/metabo10050176 |
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