Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-Based Bioprocesses

Chinese hamster ovary (CHO) cells are widely used for the production of biopharmaceuticals. Efforts to improve productivity through medium design and feeding strategy optimization have focused on preventing the depletion of essential nutrients and managing the accumulation of lactate and ammonia. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Alden, Nicholas, Raju, Ravali, McElearney, Kyle, Lambropoulos, James, Kshirsagar, Rashmi, Gilbert, Alan, Lee, Kyongbum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281457/
https://www.ncbi.nlm.nih.gov/pubmed/32429145
http://dx.doi.org/10.3390/metabo10050199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281457/
https://www.ncbi.nlm.nih.gov/pubmed/32429145
http://dx.doi.org/10.3390/metabo10050199

Ejemplares similares