Exploiting the Prevalence of Homologous Recombination Deficiencies in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) remains the most lethal gynecologic cancer in the United States. Genomic analysis revealed roughly half of HGSOC display homologous repair deficiencies. An improved understanding of the genomic and somatic mutations that influence DNA repair led to the develo...

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Detalles Bibliográficos
Autores principales: Bouberhan, Sara, Philp, Lauren, Hill, Sarah, Al-Alem, Linah F., Rueda, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281458/
https://www.ncbi.nlm.nih.gov/pubmed/32403357
http://dx.doi.org/10.3390/cancers12051206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281458/
https://www.ncbi.nlm.nih.gov/pubmed/32403357
http://dx.doi.org/10.3390/cancers12051206

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