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MicroRNA Regulation of the Small Rho GTPase Regulators—Complexities and Opportunities in Targeting Cancer Metastasis

The small Rho GTPases regulate important cellular processes that affect cancer metastasis, such as cell survival and proliferation, actin dynamics, adhesion, migration, invasion and transcriptional activation. The Rho GTPases function as molecular switches cycling between an active GTP-bound and ina...

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Detalles Bibliográficos
Autores principales: Humphries, Brock A., Wang, Zhishan, Yang, Chengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281527/
https://www.ncbi.nlm.nih.gov/pubmed/32353968
http://dx.doi.org/10.3390/cancers12051092