Different Camptothecin Sensitivities in Subpopulations of Colon Cancer Cells Correlate with Expression of Different Phospho-Isoforms of Topoisomerase I with Different Activities

The heterogeneity of tumor cells and the potential existence of rare cells with reduced chemotherapeutic response is expected to play a pivotal role in the development of drug resistant cancers. Herein, we utilized the colon cancer cell lines, Caco2 and DLD1, to investigate heterogeneity of topoisom...

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Detalles Bibliográficos
Autores principales: Tesauro, Cinzia, Keller, Josephine Geertsen, Gromova, Irina, Gromov, Pavel, Frøhlich, Rikke, Erlandsen, Jens Uldum, Andersen, Anni H., Stougaard, Magnus, Knudsen, Birgitta R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281652/
https://www.ncbi.nlm.nih.gov/pubmed/32423158
http://dx.doi.org/10.3390/cancers12051240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281652/
https://www.ncbi.nlm.nih.gov/pubmed/32423158
http://dx.doi.org/10.3390/cancers12051240

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