Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell Response

For poorly immunogenic tumors such as mesothelioma there is an imperious need to understand why antigen-presenting cells such as dendritic cells (DCs) are not prone to supporting the anticancer T cell response. The tumor microenvironment (TME) is thought to be a major contributor to this DC dysfunct...

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Detalles Bibliográficos
Autores principales: Trempolec, Natalia, Degavre, Charline, Doix, Bastien, Brusa, Davide, Corbet, Cyril, Feron, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281762/
https://www.ncbi.nlm.nih.gov/pubmed/32438640
http://dx.doi.org/10.3390/cancers12051284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281762/
https://www.ncbi.nlm.nih.gov/pubmed/32438640
http://dx.doi.org/10.3390/cancers12051284

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