Multi-Modal PET and MR Imaging in the Hen’s Egg Test-Chorioallantoic Membrane (HET-CAM) Model for Initial In Vivo Testing of Target-Specific Radioligands

The validation of novel target-specific radioligands requires animal experiments mostly using mice with xenografts. A pre-selection based on a simpler in vivo model would allow to reduce the number of animal experiments, in accordance with the 3Rs principles (reduction, replacement, refinement). In...

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Detalles Bibliográficos
Autores principales: Winter, Gordon, Koch, Andrea B. F., Löffler, Jessica, Lindén, Mika, Solbach, Christoph, Abaei, Alireza, Li, Hao, Glatting, Gerhard, Beer, Ambros J., Rasche, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281765/
https://www.ncbi.nlm.nih.gov/pubmed/32429233
http://dx.doi.org/10.3390/cancers12051248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281765/
https://www.ncbi.nlm.nih.gov/pubmed/32429233
http://dx.doi.org/10.3390/cancers12051248

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