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RGS12 Is a Novel Critical NF-κB Activator in Inflammatory Arthritis

Rheumatoid arthritis (RA) is the most common inflammatory disease, which currently lacks effective treatment. Here, we discovered that the Regulator of G Protein Signaling 12 (RGS12) plays a key role in regulating inflammation. Transcriptional and protein analysis revealed that RGS12 was upregulated...

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Detalles Bibliográficos
Autores principales: Yuan, Gongsheng, Yang, Shuting, Ng, Andrew, Fu, Chuanyun, Oursler, Merry Jo, Xing, Lianping, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281782/
https://www.ncbi.nlm.nih.gov/pubmed/32512384
http://dx.doi.org/10.1016/j.isci.2020.101172