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Automated Glycan Assembly in a Variable-Bed Flow Reactor Provides Insights into Oligosaccharide–Resin Interactions

[Image: see text] A pressure-based variable-bed flow reactor built for peptide synthesis and capable of real-time monitoring of resin swelling was adapted for automated glycan assembly. In the context of the solid-phase synthesis of several oligosaccharides, the coupling efficiencies, resin growth p...

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Detalles Bibliográficos
Autores principales: Sletten, Eric T., Danglad-Flores, José, Nuño, Manuel, Guthrie, Duncan, Seeberger, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281783/
https://www.ncbi.nlm.nih.gov/pubmed/32396006
http://dx.doi.org/10.1021/acs.orglett.0c01264