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A method for reducing animal use whilst maintaining statistical power in electrophysiological recordings from rodent nerves

The stimulus evoked compound action potential, recorded from ex vivo nerve trunks such as the rodent optic and sciatic nerve, is a popular model system used to study aspects of nervous system metabolism. This includes (1) the role of glycogen in supporting axon conduction, (2) the injury mechanisms...

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Detalles Bibliográficos
Autores principales: Rich, Laura R., Patrick, Jonathan A., Hamner, Margaret A., Ransom, Bruce R., Brown, Angus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281824/
https://www.ncbi.nlm.nih.gov/pubmed/32529085
http://dx.doi.org/10.1016/j.heliyon.2020.e04143