Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation

Activating mutations in the canonical Wnt/β-catenin pathway are key drivers of hyperplasia, the gateway for tumor development. In a wide range of tissues, this occurs primarily through enhanced effects on cellular proliferation. Whether additional mechanisms contribute to β-catenin-driven hyperplasi...

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Detalles Bibliográficos
Autores principales: Pignatti, Emanuele, Leng, Sining, Yuchi, Yixing, Borges, Kleiton S., Guagliardo, Nick A., Shah, Manasvi S., Ruiz-Babot, Gerard, Kariyawasam, Dulanjalee, Taketo, Makoto Mark, Miao, Ji, Barrett, Paula Q., Carlone, Diana L., Breault, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281829/
https://www.ncbi.nlm.nih.gov/pubmed/32320669
http://dx.doi.org/10.1016/j.celrep.2020.107524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281829/
https://www.ncbi.nlm.nih.gov/pubmed/32320669
http://dx.doi.org/10.1016/j.celrep.2020.107524

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