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Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation
Activating mutations in the canonical Wnt/β-catenin pathway are key drivers of hyperplasia, the gateway for tumor development. In a wide range of tissues, this occurs primarily through enhanced effects on cellular proliferation. Whether additional mechanisms contribute to β-catenin-driven hyperplasi...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281829/ https://www.ncbi.nlm.nih.gov/pubmed/32320669 http://dx.doi.org/10.1016/j.celrep.2020.107524 |