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Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function

BACKGROUND: Preadipocyte is closely related to obesity-induced inflammation. The impairment of autophagic flux by defective lysosomal function has been observed in adipose tissue from obese mice. While the fatty acid translocase CD36 is an important immuno-metabolic receptor, it remains unclear whet...

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Detalles Bibliográficos
Autores principales: Luo, Xiaoxiao, Li, Yanping, Yang, Ping, Chen, Yao, Wei, Li, Yu, Ting, Xia, Jun, Ruan, Xiong Z., Zhao, Lei, Chen, Yaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281849/
https://www.ncbi.nlm.nih.gov/pubmed/32516742
http://dx.doi.org/10.1016/j.ebiom.2020.102797