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Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function
BACKGROUND: Preadipocyte is closely related to obesity-induced inflammation. The impairment of autophagic flux by defective lysosomal function has been observed in adipose tissue from obese mice. While the fatty acid translocase CD36 is an important immuno-metabolic receptor, it remains unclear whet...
Autores principales: | Luo, Xiaoxiao, Li, Yanping, Yang, Ping, Chen, Yao, Wei, Li, Yu, Ting, Xia, Jun, Ruan, Xiong Z., Zhao, Lei, Chen, Yaxi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281849/ https://www.ncbi.nlm.nih.gov/pubmed/32516742 http://dx.doi.org/10.1016/j.ebiom.2020.102797 |
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