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KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis

BACKGROUND: Colorectal cancer (CRC) is the fourth most deadly malignancy throughout the world. Extensive studies have shown that Krüppel-like factors (KLFs) play essential roles in cancer development. However, the function of KLF13 in CRC is unclear. METHODS: The Cancer Genome Atlas database was app...

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Detalles Bibliográficos
Autores principales: Yao, Weilong, Jiao, Yue, Zhou, Yanhua, Luo, Xiaoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281930/
https://www.ncbi.nlm.nih.gov/pubmed/32523679
http://dx.doi.org/10.1186/s13578-020-00440-0