Cargando…
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis
BACKGROUND: Colorectal cancer (CRC) is the fourth most deadly malignancy throughout the world. Extensive studies have shown that Krüppel-like factors (KLFs) play essential roles in cancer development. However, the function of KLF13 in CRC is unclear. METHODS: The Cancer Genome Atlas database was app...
Autores principales: | Yao, Weilong, Jiao, Yue, Zhou, Yanhua, Luo, Xiaoya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281930/ https://www.ncbi.nlm.nih.gov/pubmed/32523679 http://dx.doi.org/10.1186/s13578-020-00440-0 |
Ejemplares similares
-
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis
por: Chen, Chao-Chun, et al.
Publicado: (2022) -
HMGCS2 Mediates Ketone Production and Regulates the Proliferation and Metastasis of Hepatocellular Carcinoma
por: Wang, Yuan-Hsi, et al.
Publicado: (2019) -
Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development
por: Quintana, Anita M., et al.
Publicado: (2017) -
Transcription factor KLF13 inhibits AKT activation and suppresses the growth of prostate carcinoma cells
por: Wang, Qiang, et al.
Publicado: (2018) -
CircHMGCS1 Promotes Hepatoblastoma Cell Proliferation by Regulating the IGF Signaling Pathway and Glutaminolysis
por: Zhen, Ni, et al.
Publicado: (2019)