Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD

Ever since a GGGGCC hexanucleotide repeat expansion mutation in C9ORF72 was identified as the most common cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), three competing but nonexclusive hypotheses to explain how this mutation causes diseases have been propos...

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Detalles Bibliográficos
Autores principales: Tang, Xiaoqiang, Toro, Arturo, T.G., Sahana, Gao, Junli, Chalk, Jessica, Oskarsson, Björn E., Zhang, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282082/
https://www.ncbi.nlm.nih.gov/pubmed/32513219
http://dx.doi.org/10.1186/s13024-020-00383-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282082/
https://www.ncbi.nlm.nih.gov/pubmed/32513219
http://dx.doi.org/10.1186/s13024-020-00383-7

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