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Initial dosage optimization of ciclosporin in pediatric Chinese patients who underwent bone marrow transplants based on population pharmacokinetics

Bone marrow transplants (BMT) are an established therapeutic strategy for patients with severe aplastic anemia, acute lymphoblastic leukemia, acute myeloid leukemia or chronic myeloid leukemia. However, the successful application of BMT is limited by graft-vs.-host disease (GVHD). Ciclosporin has be...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Yu, Xin, Wang, Dong-Dong, Xu, Hong, Li, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282146/
https://www.ncbi.nlm.nih.gov/pubmed/32537004
http://dx.doi.org/10.3892/etm.2020.8732