A blood RNA transcript signature for TB exposure in household contacts

BACKGROUND: Current tools for diagnosing latent TB infection (LTBI) detect immunological memory of past exposure but are unable to determine whether exposure is recent. We sought to identify a whole-blood transcriptome signature of recent TB exposure. METHODS: We studied household contacts of TB pat...

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Detalles Bibliográficos
Autores principales: Kwan, Philip Kam Weng, Periaswamy, Balamurugan, De Sessions, Paola Florez, Lin, Wenwei, Molton, James S., Naftalin, Claire M., Naim, Ahmad Nazri Mohamed, Hibberd, Martin L., Paton, Nicholas I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282166/
https://www.ncbi.nlm.nih.gov/pubmed/32517725
http://dx.doi.org/10.1186/s12879-020-05116-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282166/
https://www.ncbi.nlm.nih.gov/pubmed/32517725
http://dx.doi.org/10.1186/s12879-020-05116-1

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