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A blood RNA transcript signature for TB exposure in household contacts

BACKGROUND: Current tools for diagnosing latent TB infection (LTBI) detect immunological memory of past exposure but are unable to determine whether exposure is recent. We sought to identify a whole-blood transcriptome signature of recent TB exposure. METHODS: We studied household contacts of TB pat...

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Detalles Bibliográficos
Autores principales:	Kwan, Philip Kam Weng, Periaswamy, Balamurugan, De Sessions, Paola Florez, Lin, Wenwei, Molton, James S., Naftalin, Claire M., Naim, Ahmad Nazri Mohamed, Hibberd, Martin L., Paton, Nicholas I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282166/ https://www.ncbi.nlm.nih.gov/pubmed/32517725 http://dx.doi.org/10.1186/s12879-020-05116-1

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