Nicotinamide Inhibits Glycolysis of HL-60 Cells by Modulating Sirtuin 1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Coactivator 1α (PGC-1α)/Hypoxia-Inducible Factor-2α (HIF2α) Signaling Pathway

BACKGROUND: Nicotinamide can affect differentiation and proliferation of leukemia cells. This research aimed to explore the regulatory effect of nicotinamide on glycolysis metabolism of leukemia cells and to clarify the associated mechanisms. MATERIAL/METHODS: HL-60 cells were treated with nicotinam...

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Detalles Bibliográficos
Autores principales: Liu, Miao, Zhou, Pan, Li, Jiaojiao, Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282349/
https://www.ncbi.nlm.nih.gov/pubmed/32469848
http://dx.doi.org/10.12659/MSM.920810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282349/
https://www.ncbi.nlm.nih.gov/pubmed/32469848
http://dx.doi.org/10.12659/MSM.920810

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