The function of a heterozygous p53 mutation in a Li-Fraumeni syndrome patient

p53 is one of the most extensively studied proteins in cancer research. Mutations in p53 generally abolish normal p53 function, and some mutants can gain new oncogenic functions. However, the mechanisms underlying p53 mutation-driven cancer remains to be elucidated. Our study investigated the functi...

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Detalles Bibliográficos
Autores principales: Li, Yang, Li, Ting, Tang, Yuejia, Zhan, Zhiyan, Ding, Lixia, Song, Lili, Yu, Tingting, Yang, Yi, Ma, Jing, Zhang, Yingwen, Zhou, Ying, Gu, Song, Xu, Min, Gao, Yijin, Li, Yanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282642/
https://www.ncbi.nlm.nih.gov/pubmed/32516327
http://dx.doi.org/10.1371/journal.pone.0234262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282642/
https://www.ncbi.nlm.nih.gov/pubmed/32516327
http://dx.doi.org/10.1371/journal.pone.0234262

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