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Host cytosolic RNA sensing pathway promotes T Lymphocyte-mediated mycobacterial killing in macrophages

Mycobacterial infection leads to activation of the RIG-I/MAVS/TBK1 RNA sensing pathway in macrophages but the consequences of this activation remains poorly defined. In this study, we determined that activation of this RNA sensing pathway stimulates ICAM-1 expression in M.avium-infected macrophage t...

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Detalles Bibliográficos
Autores principales: Cheng, Yong, Kiene, Nicholas J., Tatarian, Alexandra, Eix, Emily F., Schorey, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282665/
https://www.ncbi.nlm.nih.gov/pubmed/32463840
http://dx.doi.org/10.1371/journal.ppat.1008569