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Host cytosolic RNA sensing pathway promotes T Lymphocyte-mediated mycobacterial killing in macrophages
Mycobacterial infection leads to activation of the RIG-I/MAVS/TBK1 RNA sensing pathway in macrophages but the consequences of this activation remains poorly defined. In this study, we determined that activation of this RNA sensing pathway stimulates ICAM-1 expression in M.avium-infected macrophage t...
Autores principales: | Cheng, Yong, Kiene, Nicholas J., Tatarian, Alexandra, Eix, Emily F., Schorey, Jeffrey S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282665/ https://www.ncbi.nlm.nih.gov/pubmed/32463840 http://dx.doi.org/10.1371/journal.ppat.1008569 |
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