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In silico analysis of hypoxia activated prodrugs in combination with anti angiogenic therapy through nanocell delivery
Tumour hypoxia is a well-studied phenomenon with implications in cancer progression, treatment resistance, and patient survival. While a clear adverse prognosticator, hypoxia is also a theoretically ideal target for guided drug delivery. This idea has lead to the development of hypoxia-activated pro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282674/ https://www.ncbi.nlm.nih.gov/pubmed/32463836 http://dx.doi.org/10.1371/journal.pcbi.1007926 |