The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription

Dysregulation of CDK8 (Cyclin-Dependent Kinase 8) and its regulatory partner CycC (Cyclin C), two subunits of the conserved Mediator (MED) complex, have been linked to diverse human diseases such as cancer. Thus, it is essential to understand the regulatory network modulating the CDK8-CycC complex i...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Liu, Mengmeng, Ren, Xingjie, Loncle, Nicolas, Wang, Qun, Hemba-Waduge, Rajitha-Udakara-Sampath, Yu, Stephen H., Boube, Muriel, Bourbon, Henri-Marc G., Ni, Jian-Quan, Ji, Jun-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282676/
https://www.ncbi.nlm.nih.gov/pubmed/32463833
http://dx.doi.org/10.1371/journal.pgen.1008832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282676/
https://www.ncbi.nlm.nih.gov/pubmed/32463833
http://dx.doi.org/10.1371/journal.pgen.1008832

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