Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs

Sister chromatid cohesion essential for mitotic chromosome segregation is thought to involve the co-entrapment of sister DNAs within cohesin rings. Although cohesin can load onto chromosomes throughout the cell cycle, it only builds cohesion during S phase. A key question is whether cohesion is gene...

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Detalles Bibliográficos
Autores principales: Srinivasan, Madhusudhan, Fumasoni, Marco, Petela, Naomi J, Murray, Andrew, Nasmyth, Kim A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282809/
https://www.ncbi.nlm.nih.gov/pubmed/32515737
http://dx.doi.org/10.7554/eLife.56611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282809/
https://www.ncbi.nlm.nih.gov/pubmed/32515737
http://dx.doi.org/10.7554/eLife.56611

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