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Delineating the early transcriptional specification of the mammalian trachea and esophagus

The genome-scale transcriptional programs that specify the mammalian trachea and esophagus are unknown. Though NKX2-1 and SOX2 are hypothesized to be co-repressive master regulators of tracheoesophageal fates, this is untested at a whole transcriptomic scale and their downstream networks remain unid...

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Detalles Bibliográficos
Autores principales: Kuwahara, Akela, Lewis, Ace E, Coombes, Coohleen, Leung, Fang-Shiuan, Percharde, Michelle, Bush, Jeffrey O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282815/
https://www.ncbi.nlm.nih.gov/pubmed/32515350
http://dx.doi.org/10.7554/eLife.55526