Cargando…
Delineating the early transcriptional specification of the mammalian trachea and esophagus
The genome-scale transcriptional programs that specify the mammalian trachea and esophagus are unknown. Though NKX2-1 and SOX2 are hypothesized to be co-repressive master regulators of tracheoesophageal fates, this is untested at a whole transcriptomic scale and their downstream networks remain unid...
Autores principales: | Kuwahara, Akela, Lewis, Ace E, Coombes, Coohleen, Leung, Fang-Shiuan, Percharde, Michelle, Bush, Jeffrey O |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282815/ https://www.ncbi.nlm.nih.gov/pubmed/32515350 http://dx.doi.org/10.7554/eLife.55526 |
Ejemplares similares
-
Transcriptome Dynamics in the Developing Larynx, Trachea, and Esophagus
por: Wendt, Kristy D., et al.
Publicado: (2022) -
Development of the foregut and the formation of the trachea and esophagus in rat embryos. A symphony of confusion
por: Ginzel, Marco, et al.
Publicado: (2023) -
Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting
por: Lewis, Ace E., et al.
Publicado: (2022) -
Species-Specificity of Transcriptional Regulation and the Response to Lipopolysaccharide in Mammalian Macrophages
por: Bush, Stephen J., et al.
Publicado: (2020) -
Two-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea
por: Kondo, Takefumi, et al.
Publicado: (2019)