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Maf and Mafb control mouse pallial interneuron fate and maturation through neuropsychiatric disease gene regulation

​Maf (c-Maf) and Mafb transcription factors (TFs) have compensatory roles in repressing somatostatin (SST(+)) interneuron (IN) production in medial ganglionic eminence (MGE) secondary progenitors in mice. Maf and Mafb conditional deletion (cDKO) decreases the survival of MGE-derived cortical interne...

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Detalles Bibliográficos
Autores principales: Pai, Emily Ling-Lin, Chen, Jin, Fazel Darbandi, Siavash, Cho, Frances S, Chen, Jiapei, Lindtner, Susan, Chu, Julia S, Paz, Jeanne T, Vogt, Daniel, Paredes, Mercedes F, Rubenstein, John LR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282818/
https://www.ncbi.nlm.nih.gov/pubmed/32452758
http://dx.doi.org/10.7554/eLife.54903