Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

The identification of clinically viable strategies for overcoming resistance to platinum chemotherapy in lung adenocarcinoma has previously been hampered by inappropriately tailored in vitro assays of drug response. Therefore, using a pulse model that closely mimics the in vivo pharmacokinetics of p...

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Detalles Bibliográficos
Autores principales: Hastings, Jordan F, Gonzalez Rajal, Alvaro, Latham, Sharissa L, Han, Jeremy ZR, McCloy, Rachael A, O'Donnell, Yolande EI, Phimmachanh, Monica, Murphy, Alexander D, Nagrial, Adnan, Daneshvar, Dariush, Chin, Venessa, Watkins, D Neil, Burgess, Andrew, Croucher, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282820/
https://www.ncbi.nlm.nih.gov/pubmed/32513387
http://dx.doi.org/10.7554/eLife.53367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282820/
https://www.ncbi.nlm.nih.gov/pubmed/32513387
http://dx.doi.org/10.7554/eLife.53367

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