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Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
The identification of clinically viable strategies for overcoming resistance to platinum chemotherapy in lung adenocarcinoma has previously been hampered by inappropriately tailored in vitro assays of drug response. Therefore, using a pulse model that closely mimics the in vivo pharmacokinetics of p...
Autores principales: | Hastings, Jordan F, Gonzalez Rajal, Alvaro, Latham, Sharissa L, Han, Jeremy ZR, McCloy, Rachael A, O'Donnell, Yolande EI, Phimmachanh, Monica, Murphy, Alexander D, Nagrial, Adnan, Daneshvar, Dariush, Chin, Venessa, Watkins, D Neil, Burgess, Andrew, Croucher, David R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282820/ https://www.ncbi.nlm.nih.gov/pubmed/32513387 http://dx.doi.org/10.7554/eLife.53367 |
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