ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation

BACKGROUND: Atopic dermatitis skin lesions demonstrate increased expression of IL-25 by keratinocytes and increased numbers of type 2 innate lymphoid cells (ILC2s) that express high levels of IL-25 receptor (IL-25R). IL-13 is expressed in atopic dermatitis skin lesions and plays an important role in...

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Detalles Bibliográficos
Autores principales: Leyva-Castillo, Juan Manuel, Galand, Claire, Mashiko, Shunya, Bissonnette, Robert, McGurk, Alex, Ziegler, Steven F., Dong, Chen, McKenzie, Andrew N.J., Sarfati, Marika, Geha, Raif S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282942/
https://www.ncbi.nlm.nih.gov/pubmed/32179159
http://dx.doi.org/10.1016/j.jaci.2020.02.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282942/
https://www.ncbi.nlm.nih.gov/pubmed/32179159
http://dx.doi.org/10.1016/j.jaci.2020.02.026

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