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ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation

BACKGROUND: Atopic dermatitis skin lesions demonstrate increased expression of IL-25 by keratinocytes and increased numbers of type 2 innate lymphoid cells (ILC2s) that express high levels of IL-25 receptor (IL-25R). IL-13 is expressed in atopic dermatitis skin lesions and plays an important role in...

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Detalles Bibliográficos
Autores principales:	Leyva-Castillo, Juan Manuel, Galand, Claire, Mashiko, Shunya, Bissonnette, Robert, McGurk, Alex, Ziegler, Steven F., Dong, Chen, McKenzie, Andrew N.J., Sarfati, Marika, Geha, Raif S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mosby 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282942/ https://www.ncbi.nlm.nih.gov/pubmed/32179159 http://dx.doi.org/10.1016/j.jaci.2020.02.026

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