Loss of myeloid‐specific lamin A/C drives lung metastasis through Gfi‐1 and C/EBPε‐mediated granulocytic differentiation

The immune‐suppressive tumor microenvironment promotes metastatic spread and outgrowth. One of the major contributors is tumor‐associated myeloid cells. However, the molecular mechanisms regulating their differentiation and function are not well understood. Here we report lamin A/C, a nuclear lamina...

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Detalles Bibliográficos
Autores principales: Ishii, Hiroki, Park, Woo‐Yong, So, Jaeyoung, Kuhn, Skyler, Koparde, Vishal N., Pang, Yanli, Greten, Tim F., Hollander, M. Christine, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282947/
https://www.ncbi.nlm.nih.gov/pubmed/31912614
http://dx.doi.org/10.1002/mc.23147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282947/
https://www.ncbi.nlm.nih.gov/pubmed/31912614
http://dx.doi.org/10.1002/mc.23147

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